SMT offers different C18 phases of varying carbon loads for optimal selectivity. The SMT Elite-C18 HPLC Phase is moderately hydrophobic, has carbon load comparable to most other commercially available C18 phase columns and offers faster mass transfer than SAM-OD phase. The SMT Elite-C18 columns provide excellent peak symmetry, are highly versatile and offer very good selectivity for polar and moderately non-polar pharmaceuticals and bio-molecules, with high efficiency.
The EliteC18 series contains SMT SAM-C18 phases with the intermediate functional ligand coverage, confirmed with carbon analysis results of 16% carbon load. In the EliteC18 series, the density of the functional ligand, octadecyl molecule or C18, is moderated with the proprietary spacer molecule to ensure maximum coverage. The SMT SAM-C18 phases are designed to tolerate usage in very aggressive pH conditions and high temperatures.
EliteC18 Columns are available in 5 and 10μm particle sizes and 100Å pore size, and 3.9 mm or 4.6 mm I.D.
Available SMT columns for reversed-phase chromatography include SMT-C18, SMT-C8, SMT-Elite C18, SMT-Elite C8, SMT-ODL, SMT-OL, SMT-MEB (including C1, C2, and C4), SMT-C30, SMT-C6, SMT-C12, SMT-C3, SMT-C5, SMT-Phenyl, SMT-ODAQ, SMT-OAQ, SMT-Urea, SMT-ChiralSep, SMT-CIB and other mixed phases. SMT offers many other columns for ion exchange chromatography including SMT-SAX, SMT-WAX, SMT-SCX, SMT-WCX, SMT-DEAE, SMT-MetalSep. Unlike polymer-based counterparts, these columns are silica-based and are mechanically stable at high chromatographic pressures
SMT offers packing materials for large-scale purification and Solid Phase Extraction (SPE) processes. Essentially all SMT analytical column packing materials are offered in large particle sizes at significantly reduced prices for process scale column packings and low pressure bulk purifications.
Features of the SMT EliteC18 Series:
Moderately hydrophobic
Carbon load comparable to other commercially available C18 columns
Faster mass transfer than SAM OD Series
Excellent peak symmetry
Very good selectivity for polar and moderately nonpolar pharmaceuticals and biomolecules
Versatile, designed to tolerate usage in aggressive pH conditions and high temperatures
High efficiency
Particle sizes of 5 and 10 µm are stock, others available